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Search Results for " kca3.1 channel "

5

Compounds

Cat No. Product Name Synonyms Targets
T1752 NS6180 Potassium Channel
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
T6186 TRAM-34 Triarylmethane-34,TRAM 34 Potassium Channel , IκB/IKK
TRAM-34 (Triarylmethane-34) (Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34(TRA...
T3528 Senicapoc ICA-17043 Potassium Channel
Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 =...
TP2007 Lei-Dab7 Lei-Dab 7
High affinity, selective KCa2.2 (SK2) channel blocker (Kd = 3.8 nM). Exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, IK, Kv and Kir2.1. Increases theta-burst responses and increases LTP in rat hipp...
T39283 OSK-1
OSK-1 is a potent potassium channel blocker belonging to the α-KTx3 toxins. It exhibits IC50 values of 0.6 nM, 5.4 nM, and 0.014 nM for Kv1.1, Kv1.2, and Kv1.3 channels, respectively. Additionally, OSK-1 acts as a modera...
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